Spec Care Dentist. Mineral trioxide aggregate is applied directly onto the pulp using a special applicator. 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The radiographic image in general only gives an approximation of the level of mineral content within the tissue being investigated and is limited by the fact it cannot inform with regard to the activity of the lesion nor the status of the pulp within the dentine–pulp complex. 2014b). 2013, Marques et al. European Society of Endodontology position statement: Management of deep caries and the exposed pulp. Number of times cited according to CrossRef: Bioceramic Materials in Pediatric Dentistry. (b) Carious lesion located at approximal site. If the demineralization of enamel continues to progress, dentine will be exposed to bacterial invasion, which leads to further demineralization and eventual cavitation (Bjørndal 2018). An electronic literature search included the databases PubMed, EMBASE, The Cochrane Central Register … Ridell K, Olsson H, Mejare I. Unrestored dentin caries and deep dentin restorations in Swedish adolescents. 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Findings from the present study suggest that a deep learning-based CNN algorithm can provide considerably good performance in detecting dental caries in periapical radiographs. 1996). The classification reinforces the need for a more focused or enhanced approach after carious exposure (class II), which is not as critical if the pulp is traumatically exposed (class I) due to a reduction in the microbial load close the pulp tissue. 1995). A more accurate impression of the extent of a lesion can be given on a cone‐beam computed tomograph (CBCT); however, this has limitations such as the higher dose, image distortion due to the presence of radiopaque restorations, cost and availability. 2017) and epigenetic modifying agents (Duncan et al. 1995), which can be seen strictly related to the subjacent enamel–dentine lesion complex (Bjørndal et al. In health, a mineralized shell of enamel and dentine naturally protects the pulp; however, untreated caries may progress into extremely deep lesions, inducing inflammatory pulpal reactions, leading to necrosis, abscess and eventual tooth loss (Reeves & Stanley 1966, Bergenholtz et al. Types of Studies Reviewed. In contrast, RCT was preferred in older patients (>40 years) with interproximal exposure sites. Management of deep caries and pulp capping Dr. Eason Soo DDS (UKM), MDS Endo (Hong Kong) AdvDipEndodont (Hong Kong), M Endo RCS (Edinburgh) Lecturer/Clinical Specialist in Endodontics Dept. 2013). 2015). 2000). From a scientific perspective, further understanding of the processes of inflammation, repair and material interaction is important to deepen understanding and develop novel diagnostic and therapeutic solutions. Chlorhexidine digluconate solution (2%) has been suggested as an alternative to NaOCl (Mente et al. Management of dental caries 1. The cellular events associated with reparative dentine formation are orchestrated and regulated by bioactive molecules, including growth factors (GFs), which are ‘fossilized’ in the dentine matrix (Cassidy et al. If residual carious dentine remains in situ, the dentine may shrink and potentially impair the coronal restoration, which could lead to pulpal complications (Bjørndal 2018). Stable renal function in children and adolescents with sickle cell disease after nonmyeloablative hematopoietic stem cell transplantation. 2017, World Health Organization 2017) and is costly to manage consuming an average of 5% of the overall health expenditure in industrialized and nonindustrialized countries (Petersen 2008, Listl et al. Haemostasis should be reached within 10 min. Informed power calculation: The number of treatments required to reveal a significant difference between control and experimental groups is essential. 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